Research objective: Investigation of FDG uptake in NHP brainĀ
Animal model: Female Macaca fascicularis, 4.5 kg
Acquisition protocol: PET imaging: 15 min per bed, 2 bed positions, 40 min after injection. CT imaging: 80kV, 52s per bed, 2 bed positions.
Processing and reconstruction protocol: PET: 3D OSEM, 0.84 mm isotropic voxel size. CT: 0.16 mm isotropic voxel size.
Biomarker or contrast agent: 18F-FDG; Injected activity: 85 MBq i.v.
Research objective: Study of [18F]FEOBV uptake in NHP brain
Animal model: Female Macaca fascicularis, 2.9 kg
Acquisition protocol: PET dynamic acquisition for 121 min, starting 1 min before injection
Processing and reconstruction protocol: Image reconstruction with following frames: 1x60s, 18x30s, 11x60s, 10x10min, 3D OSEM, 0.84 mm isotropic voxel size
Biomarker or contrast agent: [18F]FEOBV, 92 MBq
Image analysis: Software: PMOD v4.2. Image co-registered on a brain Macaca fascicularis MRI template (www.cermep.fr/download/atlas)
Research objective: Investigation of FDG uptake in NHP brain
Animal model: NHP, ~ 3 kg
Acquisition protocol: PET imaging: 60 min acquisition, injection right after acquisition starts. CT imaging: 80kV, 40s
Processing and reconstruction protocol: PET: 3D OSEM, 6x 10 min, 0.84 mm isotropic voxel size. CT: 0.15 mm isotropic voxel size
Biomarker or contrast agent: 18F-FDG, ~ 3 mCi
Research objective: Investigation of DOPA uptake in NHP brain
Animal model: NHP, ~ 3 kg
Acquisition protocol: PET imaging: 90 min acquisition, injection right after acquisition starts. CT imaging: 80kV, 40s
Processing and reconstruction protocol: PET: 3D OSEM, 9x 10 min, 0.84 mm isotropic voxel size. CT: 0.15 mm isotropic voxel size
Biomarker or contrast agent: 18F-DOPA, ~ 3 mCi
Research objective: Investigation of MPPF uptake in NHP brain
Animal model: NHP, ~ 3 kg
Acquisition protocol: PET imaging: 90 min acquisition, injection right after acquisition starts. CT imaging: 80kV, 40s
Processing and reconstruction protocol: PET: 3D OSEM, 9x 10 min, 0.84 mm isotropic voxel size. CT: 0.15 mm isotropic voxel size
Biomarker or contrast agent: 18F-MPPF, ~ 3 mCi