CASE 1: Mouse CT imaging with segmentation of adipose tissues

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  • Courtesy of: D.Panetta and P.A. Salvadori, IFC-CNR Pisa, Italy

Research objective:Non-enhanced micro-CT image of a mouse, showing an example of quantitative segmentation (RED = Brown Adipose Tissue - BAT; CYAN = abdominal visceral white adipose tissue - WAT; GREEN - Lungs). 

Animal model:Mouse, 20-25g

Acquisition protocol:3 min acquisition time, 1 bed position, 55 kVp, 1 mA

Processing and reconstruction protocol:0.08 mm isotropic voxel size

Biomarker or contrast agent:No tracer applied

CASE 2: Contrast enhanced CT rat imaging

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  • Courtesy of: D.Panetta and P.A. Salvadori, IFC-CNR Pisa, Italy

Research objective:Rat CT imaging with contrast enhancement

Animal model:Wistar rat, ~300g

Acquisition protocol:90 s acquisition time, 65 kVp, 1 mA, 1 bed position

Processing and reconstruction protocol:0.06 mm isotropic voxel size

Biomarker or contrast agent:Continuous infusion of Iomeron(TM), 200 mgI/ml, 24 mL/h, 8 min infusion time; CT imaging time: 0 (basal), 4 min and 8 min after beginning of infusion (3D rendering refers to 4 min)

CASE 3: Rat cardiac study

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  • Courtesy of: D.Panetta and P.A. Salvadori, IFC-CNR Pisa, Italy

Research objective: Imaging and quantification of cardiac function. Extraction of M-Mode like MPR image to visualise and quantify Left Ventricle Lateral Wall (LVLW), Left Ventricle (LV), Septum (S), Right Ventricle (RV) and Right Ventricle Lateral Wall (RVLW). Segmentation of End-Diastolic (ED) and End-Systolic (ES) to quantify End Diastolic Volume (EDV) of left ventricle, End Systolic Volume (ESV) of left ventricle, Stroke Volume (SV) and Ejection Fraction (EF).

Animal model:Wistar rat, 480g

Acquisition protocol:4 min acquisition time, 80 kVp, 1 mA, 20000 projections, 12 ms/proj

Processing and reconstruction protocol:40 gates per R-R interval, 0.24 mm isotropic voxel size

CASE 4: Ex-vivo bone study

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  • Courtesy of: Harbin Medical University, Harbin, China

Research objective:Ex-vivo study for trabecula bone structure

Animal model:Rat femur bone

Acquisition protocol:112 s acquisition time, 80 kVp, 1 mA, 2000 projections, 1 bed position

Processing and reconstruction protocol:0.06 mm isotropic voxel size